An investigation shows that proteins related to exercise can suppress tumor growth

An investigation from Edith Cowan University (ECU), in Australia, has shown that exercise can be a key weapon in the battle of cancer patients against the disea

An investigation shows that proteins related to exercise can suppress tumor growth

An investigation from Edith Cowan University (ECU), in Australia, has shown that exercise can be a key weapon in the battle of cancer patients against the disease, as the researchers publish in Medicine & Science in Sports & Exercise. .

Exercise makes the muscles segregate proteins called myoquinos, and researchers at the Medical Research Institute for the ECU exercise have discovered that these myocinies can suppress the growth of tumors and even help to actively fight cancer cells .

In a clinical trial, obese patients with prostate cancer underwent a regular training for 12 weeks and showed blood samples before and after the exercise program. Next, the researchers took the samples and applied them directly on living cells of prostate cancer.

The study supervisor, Professor Robert Newton, points out that the results help explain why cancer progresses more slowly in patients who exercise. "The levels of anticancer myocins of patients increased within three months," he reveals.

"When we take your blood before exercise and your blood after exercise and place it on living prostate cancer cells, we saw a significant suppression of the growth of those blood cells after training -Explain-. That is quite substantial and indicates That chronic exercise creates a suppressor environment of cancer in the body ".

Jin-Soo Kim, a candidate for the doctorate and leader of the investigation, affirms that, although myocinos could indicate to cancer cells that grew more slowly-or that they stopped completely, "they were unable to kill them by themselves. However, myocinies can be associated with other blood cells to actively fight against cancer.

"The myocins, by themselves, do not indicate to the cells that die -Precise Kim-. But they indicate to our immune cells -The T-cells attack and kill cancer cells."

For its part, Professor Newton adds that exercise also complements other prostate cancer treatments, such as androgen deprivation therapy, which is effectively prescribed, but that can also cause a significant reduction in lean mass and a Increase in fat mass. This can lead to sarcopene obesity (obese with little muscle mass), worse health and cancer results.

All participants in the study were subjected to TDA and were obese, and the training program allowed them to maintain lean mass while losing fat mass.

The study focused on prostate cancer, because it is the most frequent among men and by the high number of patient deaths, but Professor Newton ensures that the results could have a broader repercussion. "We believe that this mechanism is applicable to all types of cancer," he says.

The ECU is carrying out other studies, including an essay in which patients with advanced phase prostate cancer undergo a six-month exercise program.

Although the results are still pending, Professor Newton advances that the preliminary results are encouraging. "These men have a great burden of disease, broad side effects of treatment and are very bad, but they can still produce cancer medications from within. It is important since it can indicate why men, even with advanced cancer, if they are physically Assets, do not succumb so quickly, "stands out.

Updated Date: 15 October 2021, 17:52

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