Mary Lou McDonald, president of Sinn Fein, has stated that her party will present a motion to no confidence in the Irish government on Monday.
After Joe McHugh's resignation as Fine Gael whip, the coalition government has lost its majority in the Dail (lower chamber of parliament).
The government currently has 79 TDs, one less than a majority.
McHugh quit the whip due to concerns over a scheme that would allow owners of defective houses to get their money back.
He stated that he felt the homeowner redress program for those whose homes have been destroyed by blocks of pyrite or mica was not accessible and affordable.
Ms. McDonald confirmed Friday that Sinn Fein would press for a vote, which would lead to the government's collapse if it loses.
She added that "This government lost its majority in parliament, failed to address the housing and cost of living crises"
"This government is out-of-touch and out of time.
"We need a government which puts families and workers first."
Ms. McDonald said to RTE that the government had lost touch with the Irish broadcaster.
By Shane Harrison, BBC News NI Dublin Correspondent
Despite the motion to no confidence in his coalition government Taoiesach (Irish Prime Minster) Micheal Mart is unlikely to follow the path of Boris Johnson.
While his three-party government has already won support from 79 of the 159 candidates, it has been able to rely on several independents, including two.
Mary Lou McDonald, Sinn Fein leader, is appealing to all independents to "do the right thing" when she sees it.
It's a appeal that will likely fall on deaf ears.
The drama at Leinster House next Wednesday will be almost as dramatic as that at Westminster this week.
Fianna Fail and Fine Gael form the governing coalition, while some independent politicians also supported it in Dail votes.
Independent TD for Clare Michael McNamara stated that he would not support the government in the vote of no confidence.
McNamara stated that the government is failing to address the problems it could control.
Leo Varadkar, the Deputy Prime Minister of Ireland, stated earlier that he was certain Mr McHugh would vote for the government on other issues. Therefore, it would have a working majority.
