Uruguay leads the all-time string between both sides, with a record of 32-25-17, and hasn't lost to Paraguay since a World Cup qualifier in 2007--a span of seven games. Uruguay won their last assembly in a World Cup qualifier in 2017.
Uruguay has been inconsistent in qualifying thus far, appreciating the highs of wins over Chile and Colombia while enduring the highs of defeats to Ecuador and Brazil. Paraguay, meanwhile, has yet to lose, beating Venezuela and tying Peru, Argentina and Bolivia. The game pits two of the highest scorers in World Cup qualifying against one another, with Paraguay's Ángel Romero and Uruguay's Luis Suárez both netting four goals in the opening four matches.
Both sides will meet again in late June to shut group play in Copa América, which has been transferred to Brazil following the first plans for it to be staged throughout Argentina and Colombia.